Creating a Soothing Bedtime Routine – 7 Tips to Meet the Challenge

For toddlers and preschoolers, the bedtime routine can often be the most challenging part of the day. It means another transition and separation from you, at the same time that everyone in the household is a bit tired and sometimes frazzled from a long day.

Every parent knows that bedtime routines should be soothing and predictable for their child. Dr. Douglas Teti, a Professor of Human Development and Family Studies from Penn State published a finding about the importance of bedtime routines. He studied 35 parents with children under 2 years old. Granted, not a huge study but his findings were validating. Dr. Teti states that children sleep better when their emotional needs were met and they felt attached to their parents. In other words, the parents needed to be:

  • somewhat flexible in their routine (ie. mix it up with a puzzle one night instead of a book)
  • responsive to their child’s needs at that particular moment, and
  • the parent’s words and actions should match their behavior.

When parents are emotionally available their children feel more secure and safe and are able to go to sleep more easily.

I always swore that if I was feeling a bit frazzled at bedtime or if I was in a rush at bedtime, my girls picked it up and the bedtime routine didn’t go as smoothly. Children are so intuitive! Without realizing it our children teach us to be in the moment …

RespireRx Explores Commercialization of Dronabinol for Treatment of Obstructive Sleep Apnea in Australia, New Zealand, Southeast Asia

RespireRx Pharmaceuticals Inc, which is researching and developing cannabinoids for the treatment of sleep-related breathing disorders, has entered into a non-binding memorandum of understanding and exclusivity agreement with Impression Healthcare Ltd. The non-binding memo is for the purpose of negotiating terms by which the parties would enter in an arrangement, such as a license, joint venture, or partner agreement, so as to commercialize dronabinol for the treatment of obstructive sleep apnea (OSA) in Australia, New Zealand, and Southeast Asia.

To date, RespireRx has focused on dronabinol development in the United States. However, Australia also represents a potentially significant market opportunity. According to SNORE Australia, approximately 9% of women and 25% of men in Australia have clinically significant OSA.

As an alternative to CPAP, Impression currently markets and sells the Sleep Guardian Dorsal, a dental mandibular advancement device, which is sold through the company’s Preferred Practitioner Network. On December 4, 2018, Impression disclosed its intentions for commercializing dronabinol for certain indications and on February 15, 2019, disclosed its discussions with RespireRx about OSA.

The initial intent of the parties is to create an appropriate commercial vehicle in order to rapidly introduce dronabinol to the Australian market through the Special Access Scheme, which permits, under certain circumstances, prescriptions of identified unregistered drug products. It is anticipated that this potentially rapid commercialization will be followed by the introduction of a registered product following the completion of RespireRx’s planned phase 3 clinical trial program

Supine Sleep Linked to Neurodegenerative Disease

Could sleeping on your back increase the risk of developing neurodegenerative disease? A study published in the Journal of Alzheimer’s Disease provides new insights on this subject.

“We compared the in-home sleep patterns of patients with memory impairment resulting from neurodegenerative diseases to a large group of elderly with normal cognition,” says Daniel J. Levendowski, the study’s first author and president of Advanced Brain Monitoring, in a release. “Sleeping more than 2 hours with one’s head lying face upward (ie, supine) was a significant nocturnal marker that characterized those with memory impairment, after controlling for factors such as age, sex, snoring, obstructive sleep apnea, and movements during the night.”

These results corroborate in humans a finding observed in rats by researchers at Stony Brook University and published in the Journal of Neuroscience. Using dynamic contrast MRI, the Stony Brook researchers found that the clearance of neurotoxic proteins from the brain by glymphatic transport was less efficient when the rats’ heads were in the supine sleep position. “Our results clearly support their conclusions,” says Philip R. Westbrook, MD, chief medical officer of Advanced Brain Monitoring. “We also suggest how the interaction between supine sleep and the natural changes that come with age could impact the clearance of β-amyloid, tau, alpha-synuclein, and other neurotoxins from the brain during sleep.”

Because imaging of the glymphatic system in humans is not yet possible, additional research is needed to establish whether the relationship between

Nasal Pillow Interfaces Evolve

New launches showcase trends such as minimal face contact, noise reducing technology, and a natural feel.

Some sleep apnea patients will tell you that it’s not always easy to sleep with a CPAP mask. Escaping air can create a loud hissing noise that wakes them up during the night. The headgear can feel claustrophobic and restrictive. Tight straps that keep the mask securely in place can dig into the skin and leave marks the next morning. Some patients may find that nasal pillow masks are less bulky, make minimal contact with the face, and allow them to move more freely. These masks continue to evolve, offering lighter, more comfortable interfaces.

“I find that a lot of patients are pulling away from the full facemask. They want the very small, petite, noninvasive, nonintrusive, nasal masks,” says Russell Rozensky, MS, RRT-SDS, CPFT, RPSGT, program director at The Stony Brook School of Health Technology and Management’s Polysomnographic Technology Program in New York.

“A lot of the full facemasks cause a certain level of anxiety for patients and with the new nasal pillows, and the smaller nasal interfaces, it makes it a lot more comfortable for patients to sleep with,” says Rozensky.

When working with a new patient, Rozensky will first have them try a nasal pillow mask. If there isn’t enough pressure or if the sleep apnea is severe, he might move them to a full face mask, but then

Specific Obstructive Sleep Apnea Subtype at Greatest Risk of Cardiovascular Disease

Adults with obstructive sleep apnea (OSA) who experience excessive sleepiness while awake appear to be at far greater risk for cardiovascular diseases than those without excessive daytime sleepiness, according to new research published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.

In “Symptom Subtypes of Obstructive Sleep Apnea Predict Incidence of Cardiovascular Outcomes,” Diego R. Mazzotti, PhD, and coauthors report on a study of adults with moderate to severe OSA who were categorized into 4 subtypes according to the symptoms they report: disturbed sleep, minimally symptomatic, moderately sleepy, and excessively sleepy.

Previous studies have linked OSA and cardiovascular disease. To understand this association better, researchers have begun to categorize patients with OSA based on their symptoms.

“Multiple studies from our group have shown that patients with moderate to severe OSA throughout the world can be categorized into specific subtypes based on their reported symptoms,” says Mazzotti, lead study author and a sleep researcher at the University of Pennsylvania. “However, until now, it was unclear whether these subtypes had different clinical consequences, especially in regard to future cardiovascular risk.”

The current study analyzed data from 1,207 adults participating in the Sleep Heart Health Study, available from the National Sleep Research Resource. Patients were 40 years old or older at enrollment and were followed for nearly 12 years. The patients had moderate to severe OSA, which was defined as having at least 15

Can Snoring Be Stopped?

It is interesting that many people get easily annoyed when they hear the loud snoring sounds from sleeping snorers when in reality 1/2 of all adults actually snore. We are speaking of millions of individuals who emit snore sounds once they sleep at night. From your youth until the present, you probably know so many people who are guilty of snoring and the majority of us eventually accepted snoring as part of the norm.

Unfortunately, along with snoring are its medical risks that endanger the snorer’s life and make the life of the non-snoring partner miserable as they endure long and sleepless nights without reprieve from their snoring partner’s annoying nighttime habit.

Snorers may suffer from daytime fatigue, chronic sleeplessness, and sleep deprivation as their sleep quality deteriorates every single night. The airway is blocked and the snorer often gasps for air in their sleep. They experience constant breathing gaps now and then that makes it difficult for the body to pump life-giving oxygen to the brain and the other parts of the body, which can affect certain body functions negatively over time.

There are two types of snorers: Those who know they snore (a partner or family member told them so) and those who think they sleep soundly … But don’t.

Nearly half of all adults snore, which is bad news for their partners and their general health. The body’s reactions to snoring can lead to disrupted sleep

Surgery to Move Jaws Improves Outcomes in Obstructive Sleep Apnea Patients

Surgery that moves both jaws forward—known as maxillomandibular advancement (MMA)—is a significantly effective and safe treatment for obstructive sleep apnea (OSA), resulting in benefits that include improved breathing, daytime wakefulness and quality of life, as well as a lower cardiovascular risk, according to a new study.

MMA should be regarded as the preferred treatment for patients with moderate to severe OSA who cannot stick with the treatment of continuous positive airway pressure (CPAP) or declined CPAP as a long-term treatment, researchers concluded in the study published in the February issue of the Journal of Oral and Maxillofacial Surgerythe official journal of the American Association of Oral and Maxillofacial Surgeons (AAOMS).

During OSA, airway muscles, large tonsils, the tongue, or excess tissue obstruct the airway, resulting in breathing dangerously stopping and starting during sleep. The condition can result in excessive daytime sleepiness, lower quality of life, and impaired cognitive function that impacts daily activities. The sleep disorder is associated with high blood pressure, diabetes, and cardiovascular disease. CPAP, the standard accepted therapy for OSA, blows air to keep the airways open.

The multicenter study included 30 adult patients with severe OSA, most of them overweight and male, who underwent MMA because they were unable to continue CPAP therapy or they declined to use CPAP long term. Data were recorded before and after surgery.

After patients underwent MMA, researchers found the patients experienced significant improvements in sleep-disordered breathing, sleepiness, sleep-specific

Too Much, Too Little Sleep Linked to Increased Cardiovascular Disease Risk

The amount of time you sleep, including daytime naps, is linked to your risk of developing cardiovascular disease and death, according to a study of over 116,000 people in 7 regions of the world, published in the European Heart Journal.

The researchers found that people who slept for longer than the recommended duration of 6 to 8 hours a day had an increased risk of dying or developing diseases of the heart or blood vessels in the brain. Compared to people who slept for the recommended time, those who slept a total of 8 to 9 hours a day had a 5% increased risk; people sleeping between 9 and 10 hours a day had an increased risk of 17% and those sleeping more than ten hours a day had a 41% increased risk. They also found a 9% increased risk for people who slept a total of 6 or fewer hours, but this finding was not statistically significant.

Before adjusting for factors that might affect the results, the researchers found that for every 1000 people sleeping six or fewer hours a night, 9.4 developed cardiovascular disease (CVD) or died per year; this occurred in 7.8 of those sleeping 6 to 8 hours, 8.4 of those sleeping 8 to 9 hours, 10.4 of those sleeping 9 to 10 hours and 14.8 of those sleeping more than 10 hours.

The lead author of the publication, Chuangshi Wang, a PhD student at